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The original Sore No More Warm
Therapy
crème has 0.03% plant extract “Capsacini” which is
derived from a plant in the Chilli Family. Capsaicin
selectively binds to a protein known as
TRPV1
that resides on the membranes of pain and heat sensing
neurons. TRPV1 is a heat activated calcium channel,
which opens between 37 and 45
°C.
When capsaicin binds to TRPV1, it causes the channel to
open below 37 °C (normal
human body temperature),
which is why capsaicin is linked to the sensation of
heat.
Capsaicin
is used in topical
ointments
to relieve the pain of peripheral neuropathy.
In concentrations of between 0.025% and 0.075%. It can
be used as a cream for the temporary relief of minor
aches and pains of
muscles
and joints associated with
arthritis,
simple backache, strains and
sprains.
Capsicine is one of the very few natural pain relievers
recommended by the Arthritis council. A PDF clinical
report can be downloaded from the
council's website
The New COOL Sore No More
does not contain any alcohol and derives it cooling and
analgesic properties from Menthol (U.S.P 6.0%).
Menthol's ability to chemically trigger the
cold-sensitive
TRPM8
receptors in the skin is responsible for the well known
cooling sensation that it provokes when applied. In this
sense it is similar to
capsaicin,
the chemical responsible for the spiciness of hot
peppers (which stimulates
heat sensors,
also without causing an actual change in temperature).
Both
versions of Sore No More are 100% natural, and are
therefore suitable for use by patients that are
vegetarian/vegan and those who have religious or ethical
dispositions to alcohol. |
